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Deciphering physiological role of the mechanosensitive TRPV4 channel in the distal nephron

Long-standing experimental evidence suggests that epithelial cells in the renal tubule are able to sense osmotic and pressure gradients caused by alterations in ultrafiltrate flow by elevating intracellular Ca(2+) concentration. These responses are viewed as critical regulators of a variety of proce...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Mamenko, M., Zaika, O., Boukelmoune, N., O'Neil, R. G., Pochynyuk, O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329491/
https://ncbi.nlm.nih.gov/pubmed/25503733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00485.2014
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