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Emerging Role of the Calcium-Activated, Small Conductance, SK3 K(+) Channel in Distal Tubule Function: Regulation by TRPV4

The Ca(2+)-activated, maxi-K (BK) K(+) channel, with low Ca(2+)-binding affinity, is expressed in the distal tubule of the nephron and contributes to flow-dependent K(+) secretion. In the present study we demonstrate that the Ca(2+)-activated, SK3 (K(Ca)2.3) K(+) channel, with high Ca(2+)-binding af...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Berrout, Jonathan, Mamenko, Mykola, Zaika, Oleg L., Chen, Lihe, Zang, Wenzheng, Pochynyuk, Oleh, O'Neil, Roger G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3999037/
https://ncbi.nlm.nih.gov/pubmed/24762817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095149
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