Llwytho...
Antisense-mediated angiotensinogen inhibition slows polycystic kidney disease in mice with a targeted mutation in Pkd2
Renal cyst enlargement is associated with the activation of both the circulating and intrarenal renin-angiotensin systems. Angiotensinogen (AGT) is the substrate for renin. The aim of the present study was to determine the effect of AGT inhibition on renal cyst enlargement. An AGT antisense oligonuc...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Am J Physiol Renal Physiol |
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| Prif Awduron: | , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
American Physiological Society
2014
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4329486/ https://ncbi.nlm.nih.gov/pubmed/25537744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00478.2014 |
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