Suppressing angiotensinogen synthesis attenuates kidney cyst formation in a Pkd1 mouse model

Activation of the intrarenal renin angiotensin system (RAS) is believed to play an important role in the development of hypertension and cystogenesis in autosomal dominant polycystic kidney disease (ADPKD). Results of clinical studies testing RAS inhibitors in slowing the progression of cystic disea...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:FASEB J
Asıl Yazarlar: Saigusa, Takamitsu, Dang, Yujing, Mullick, Adam E., Yeh, Steve T., Zile, Michael R., Baicu, Catalin F., Bell, P. Darwin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Federation of American Societies for Experimental Biology 2016
Konular:
Research Communication
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684522/
https://ncbi.nlm.nih.gov/pubmed/26391272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-279299
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