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Suppressing angiotensinogen synthesis attenuates kidney cyst formation in a Pkd1 mouse model
Activation of the intrarenal renin angiotensin system (RAS) is believed to play an important role in the development of hypertension and cystogenesis in autosomal dominant polycystic kidney disease (ADPKD). Results of clinical studies testing RAS inhibitors in slowing the progression of cystic disea...
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| Veröffentlicht in: | FASEB J |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Federation of American Societies for Experimental Biology
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4684522/ https://ncbi.nlm.nih.gov/pubmed/26391272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-279299 |
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