Micro-RNA 21 inhibition of SMAD7 enhances fibrogenesis via leptin-mediated NADPH oxidase in experimental and human nonalcoholic steatohepatitis

Hepatic fibrosis in nonalcoholic steatohepatitis (NASH) is the common pathophysiological process resulting from chronic liver inflammation and oxidative stress. Although significant research has been carried out on the role of leptin-induced NADPH oxidase in fibrogenesis, the molecular mechanisms th...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Am J Physiol Gastrointest Liver Physiol
Main Authors: Dattaroy, Diptadip, Pourhoseini, Sahar, Das, Suvarthi, Alhasson, Firas, Seth, Ratanesh Kumar, Nagarkatti, Mitzi, Michelotti, Gregory A., Diehl, Anna Mae, Chatterjee, Saurabh
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2014
Assuntos:
Liver and Biliary Tract
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329476/
https://ncbi.nlm.nih.gov/pubmed/25501551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00346.2014
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares