Expression, purification, crystallization, and preliminary X-ray crystallographic studies of the human adiponectin receptors, AdipoR1 and AdipoR2

The adiponectin receptors (AdipoR1 and AdipoR2) are membrane proteins with seven transmembrane helices. These receptors regulate glucose and fatty acid metabolism, thereby ameliorating type 2 diabetes. The full-length human AdipoR1 and a series of N-terminally truncated mutants of human AdipoR1 and...

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Vydáno v:J Struct Funct Genomics
Hlavní autoři: Tanabe, Hiroaki, Motoyama, Kanna, Ikeda, Mariko, Wakiyama, Motoaki, Terada, Takaho, Ohsawa, Noboru, Hosaka, Toshiaki, Hato, Masakatsu, Fujii, Yoshifumi, Nakamura, Yoshihiro, Ogasawara, Satoshi, Hino, Tomoya, Murata, Takeshi, Iwata, So, Okada-Iwabu, Miki, Iwabu, Masato, Hirata, Kunio, Kawano, Yoshiaki, Yamamoto, Masaki, Kimura-Someya, Tomomi, Shirouzu, Mikako, Yamauchi, Toshimasa, Kadowaki, Takashi, Yokoyama, Shigeyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329188/
https://ncbi.nlm.nih.gov/pubmed/25575462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10969-014-9192-z
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