Expression, purification, crystallization, and preliminary X-ray crystallographic studies of the human adiponectin receptors, AdipoR1 and AdipoR2

The adiponectin receptors (AdipoR1 and AdipoR2) are membrane proteins with seven transmembrane helices. These receptors regulate glucose and fatty acid metabolism, thereby ameliorating type 2 diabetes. The full-length human AdipoR1 and a series of N-terminally truncated mutants of human AdipoR1 and...

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Pubblicato in:J Struct Funct Genomics
Autori principali: Tanabe, Hiroaki, Motoyama, Kanna, Ikeda, Mariko, Wakiyama, Motoaki, Terada, Takaho, Ohsawa, Noboru, Hosaka, Toshiaki, Hato, Masakatsu, Fujii, Yoshifumi, Nakamura, Yoshihiro, Ogasawara, Satoshi, Hino, Tomoya, Murata, Takeshi, Iwata, So, Okada-Iwabu, Miki, Iwabu, Masato, Hirata, Kunio, Kawano, Yoshiaki, Yamamoto, Masaki, Kimura-Someya, Tomomi, Shirouzu, Mikako, Yamauchi, Toshimasa, Kadowaki, Takashi, Yokoyama, Shigeyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Netherlands 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329188/
https://ncbi.nlm.nih.gov/pubmed/25575462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10969-014-9192-z
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