Cargando...
Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1
Telomere maintenance by telomerase is impaired in the stem cell disease dyskeratosis congenita and during human aging. Telomerase depends upon a complex pathway for enzyme assembly, localization in Cajal bodies and association with telomeres. Here, we identify the chaperonin CCT/TRiC as a critical r...
Gardado en:
| Publicado en: | Cell |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4329143/ https://ncbi.nlm.nih.gov/pubmed/25467444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.10.059 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|