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Identification of ATPases pontin and reptin as telomerase components essential for holoenzyme assembly
Telomerase is a multi-subunit ribonucleoprotein (RNP) complex that adds telomere repeats to the ends of linear chromosomes. Three essential telomerase components have been identified thus far: the telomerase reverse transcriptase (TERT), the telomerase RNA component (TERC), and the TERC-binding prot...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2291539/ https://ncbi.nlm.nih.gov/pubmed/18358808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.01.019 |
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