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Identification of ATPases pontin and reptin as telomerase components essential for holoenzyme assembly

Telomerase is a multi-subunit ribonucleoprotein (RNP) complex that adds telomere repeats to the ends of linear chromosomes. Three essential telomerase components have been identified thus far: the telomerase reverse transcriptase (TERT), the telomerase RNA component (TERC), and the TERC-binding prot...

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Autors principals: Venteicher, Andrew S., Meng, Zhaojing, Mason, Philip J., Veenstra, Timothy D., Artandi, Steven E.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291539/
https://ncbi.nlm.nih.gov/pubmed/18358808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.01.019
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