An activity switch in human telomerase based on RNA conformation and shaped by TCAB1

Ribonucleoprotein enzymes require dynamic conformations of their RNA constituents for regulated catalysis. Human telomerase employs a non-coding RNA (hTR) with a bipartite arrangement of domains - a template-containing core and a distal three-way junction (CR4/5) that stimulates catalysis through un...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell
Main Authors: Chen, Lu, Roake, Caitlin M., Freund, Adam, Batista, Pedro J., Tian, Siqi, Yin, Yi A., Gajera, Chandresh R., Lin, Shengda, Lee, Byron, Pech, Matthew F., Venteicher, Andrew S., Das, Rhiju, Chang, Howard Y., Artandi, Steven E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063371/
https://ncbi.nlm.nih.gov/pubmed/29804836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.04.039
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados