The NHLBI-Sponsored Consortium for preclinicAl assESsment of cARdioprotective Therapies (CAESAR): A New Paradigm for Rigorous, Accurate, and Reproducible Evaluation of Putative Infarct-Sparing Interventions in Mice, Rabbits, and Pigs

RATIONALE: Despite four decades of intense effort and substantial financial investment, the cardioprotection field has failed to deliver a single drug that effectively reduces myocardial infarct size in patients. A major reason is insufficient rigor and reproducibility in preclinical studies. OBJECT...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Jones, Steven P., Tang, Xian-Liang, Guo, Yiru, Steenbergen, Charles, Lefer, David J., Kukreja, Rakesh C., Kong, Maiying, Li, Qianhong, Bhushan, Shashi, Zhu, Xiaoping, Du, Junjie, Nong, Yibing, Stowers, Heather L., Kondo, Kazuhisa, Hunt, Gregory N., Goodchild, Traci T., Orr, Adam, Chang, Carlos C., Ockaili, Ramzi, Salloum, Fadi N., Bolli, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329104/
https://ncbi.nlm.nih.gov/pubmed/25499773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.305462
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados