The NHLBI-Sponsored Consortium for preclinicAl assESsment of cARdioprotective Therapies (CAESAR): A New Paradigm for Rigorous, Accurate, and Reproducible Evaluation of Putative Infarct-Sparing Interventions in Mice, Rabbits, and Pigs

RATIONALE: Despite four decades of intense effort and substantial financial investment, the cardioprotection field has failed to deliver a single drug that effectively reduces myocardial infarct size in patients. A major reason is insufficient rigor and reproducibility in preclinical studies. OBJECT...

詳細記述

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書誌詳細
出版年:Circ Res
主要な著者: Jones, Steven P., Tang, Xian-Liang, Guo, Yiru, Steenbergen, Charles, Lefer, David J., Kukreja, Rakesh C., Kong, Maiying, Li, Qianhong, Bhushan, Shashi, Zhu, Xiaoping, Du, Junjie, Nong, Yibing, Stowers, Heather L., Kondo, Kazuhisa, Hunt, Gregory N., Goodchild, Traci T., Orr, Adam, Chang, Carlos C., Ockaili, Ramzi, Salloum, Fadi N., Bolli, Roberto
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329104/
https://ncbi.nlm.nih.gov/pubmed/25499773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.305462
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