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Vascular BK channel deficiency exacerbates organ damage and mortality in endotoxemic mice
We determined the contribution of vascular BK channels to endotoxin (lipopolysaccharide, LPS)-induced hypotension, organ damage, and mortality using smooth muscle BK channel deficiency (BK channel β1-subunit knockout, BK β1-KO) mice. BK β1-KO mice were more sensitive to LPS-induced mortality compare...
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| Vydáno v: | J Cardiovasc Pharmacol |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4327844/ https://ncbi.nlm.nih.gov/pubmed/21997262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0b013e31823b493b |
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