Coexistent hyperdiploidy does not abrogate poor prognosis in myeloma with adverse cytogenetics and may precede IGH translocations

The acquisition of the cytogenetic abnormalities hyperdiploidy or translocations into the immunoglobulin gene loci are considered as initiating events in the pathogenesis of myeloma and were often assumed to be mutually exclusive. These lesions have clinical significance; hyperdiploidy or the presen...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Blood
Huvudupphovsmän: Pawlyn, Charlotte, Melchor, Lorenzo, Murison, Alex, Wardell, Christopher P., Brioli, Annamaria, Boyle, Eileen M., Kaiser, Martin F., Walker, Brian A., Begum, Dil B., Dahir, Nasrin B., Proszek, Paula, Gregory, Walter M., Drayson, Mark T., Jackson, Graham H., Ross, Fiona M., Davies, Faith E., Morgan, Gareth J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2015
Ämnen:
Lymphoid Neoplasia
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4327151/
https://ncbi.nlm.nih.gov/pubmed/25428216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-07-584268
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk