Lifespan-extending caloric restriction or mTOR inhibition impair adaptive immunity of old mice by distinct mechanisms

Aging of the world population and a concomitant increase in age-related diseases and disabilities mandates the search for strategies to increase healthspan, the length of time an individual lives healthy and productively. Due to the age-related decline of the immune system, infectious diseases remai...

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Bibliografiske detaljer
Udgivet i:Aging Cell
Main Authors: Goldberg, Emily L, Romero-Aleshire, Melissa J, Renkema, Kristin R, Ventevogel, Melissa S, Chew, Wade M, Uhrlaub, Jennifer L, Smithey, Megan J, Limesand, Kirsten H, Sempowski, Gregory D, Brooks, Heddwen L, Nikolich-Žugich, Janko
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2015
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326902/
https://ncbi.nlm.nih.gov/pubmed/25424641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12280
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