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PRENATAL TESTOSTERONE EXPOSURE INDUCES HYPERTENSION IN ADULT FEMALES VIA ANDROGEN RECEPTOR-DEPENDENT PKCδ-MEDIATED MECHANISM
Prenatal exposure to excess testosterone induces hyperandrogenism in adult females and predisposes them to hypertension. We tested whether androgens induce hypertension through transcriptional regulation and signaling of protein kinase C (PKC) in the mesenteric arteries. Pregnant Sprague-Dawley rats...
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| Publicado no: | Hypertension |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4326589/ https://ncbi.nlm.nih.gov/pubmed/25489059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.114.04521 |
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