PRENATAL TESTOSTERONE EXPOSURE INDUCES HYPERTENSION IN ADULT FEMALES VIA ANDROGEN RECEPTOR-DEPENDENT PKCδ-MEDIATED MECHANISM

Prenatal exposure to excess testosterone induces hyperandrogenism in adult females and predisposes them to hypertension. We tested whether androgens induce hypertension through transcriptional regulation and signaling of protein kinase C (PKC) in the mesenteric arteries. Pregnant Sprague-Dawley rats...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Hypertension
Prif Awduron: Blesson, Chellakkan S., Chinnathambi, Vijayakumar, Hankins, Gary D., Yallampalli, Chandra, Sathishkumar, Kunju
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326589/
https://ncbi.nlm.nih.gov/pubmed/25489059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.114.04521
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