Gestational Exposure to Elevated Testosterone Levels Induces Hypertension via Heightened Vascular Angiotensin II Type 1 Receptor Signaling in Rats

Pre-eclampsia is a life-threatening pregnancy disorder whose pathogenesis remains unclear. Plasma testosterone levels are elevated in pregnant women with pre-eclampsia and polycystic ovary syndrome, who often develop gestational hypertension. We tested the hypothesis that increased gestational testo...

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Publicado en:Biol Reprod
Main Authors: Chinnathambi, Vijayakumar, More, Amar S., Hankins, Gary D., Yallampalli, Chandra, Sathishkumar, Kunju
Formato: Artigo
Idioma:Inglês
Publicado: Society for the Study of Reproduction, Inc. 2014
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4434963/
https://ncbi.nlm.nih.gov/pubmed/24855104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.114.118968
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