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PRENATAL TESTOSTERONE EXPOSURE INDUCES HYPERTENSION IN ADULT FEMALES VIA ANDROGEN RECEPTOR-DEPENDENT PKCδ-MEDIATED MECHANISM
Prenatal exposure to excess testosterone induces hyperandrogenism in adult females and predisposes them to hypertension. We tested whether androgens induce hypertension through transcriptional regulation and signaling of protein kinase C (PKC) in the mesenteric arteries. Pregnant Sprague-Dawley rats...
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| Udgivet i: | Hypertension |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4326589/ https://ncbi.nlm.nih.gov/pubmed/25489059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.114.04521 |
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