IL-23 activates innate lymphoid cells to promote neonatal intestinal pathology

Interleukin-23 (IL-23) responsive group 3 innate lymphoid cells (ILC3s) have been implicated in immune homeostasis and pathogenesis in the adult, but little is known about their roles in the newborn. Here we show that IL-23 promotes conversion of embryonic intestinal Lin(−)IL-23R(+)Thy1(+) cells int...

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Vydáno v:Mucosal Immunol
Hlavní autoři: Chen, Lili, He, Zhengxiang, Slinger, Erik, Bongers, Gerold, Lapenda, Taciana L.S., Pacer, Michelle E., Jiao, Jingjing, Beltrao, Monique F., Soto, Alan J., Harpaz, Noam, Gordon, Ronald E., Ochando, Jordi C., Oukka, Mohamed, Iuga, Alina Cornelia, Chensue, Stephen W., Blander, Julie Magarian, Furtado, Glaucia C., Lira, Sergio A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326561/
https://ncbi.nlm.nih.gov/pubmed/25160819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2014.77
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