TNFα-dependent development of lymphoid tissue in the absence of RORγt(+) Lymphoid Tissue Inducer cells

Lymphoid tissue often forms within sites of chronic inflammation. Here we report that expression of the proinflammatory cytokine TNFa drives development of lymphoid tissue in the intestine. Formation of this ectopic lymphoid tissue was not dependent on the presence of canonical RORgt(+) lymphoid tis...

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Udgivet i:Mucosal Immunol
Main Authors: Furtado, Glaucia C., Pacer, Michelle E., Bongers, Gerold, Benezech, Cecile, He, Zhengxiang, Chen, Lili, Berin, M Cecilia, Kollias, George, Caamaño, Jorge H., Lira, Sergio A.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264842/
https://ncbi.nlm.nih.gov/pubmed/24129162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2013.79
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