IL-23 activates innate lymphoid cells to promote neonatal intestinal pathology

Interleukin-23 (IL-23) responsive group 3 innate lymphoid cells (ILC3s) have been implicated in immune homeostasis and pathogenesis in the adult, but little is known about their roles in the newborn. Here we show that IL-23 promotes conversion of embryonic intestinal Lin(−)IL-23R(+)Thy1(+) cells int...

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Detalles Bibliográficos
Publicado en:Mucosal Immunol
Main Authors: Chen, Lili, He, Zhengxiang, Slinger, Erik, Bongers, Gerold, Lapenda, Taciana L.S., Pacer, Michelle E., Jiao, Jingjing, Beltrao, Monique F., Soto, Alan J., Harpaz, Noam, Gordon, Ronald E., Ochando, Jordi C., Oukka, Mohamed, Iuga, Alina Cornelia, Chensue, Stephen W., Blander, Julie Magarian, Furtado, Glaucia C., Lira, Sergio A.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326561/
https://ncbi.nlm.nih.gov/pubmed/25160819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2014.77
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