IL-23 activates innate lymphoid cells to promote neonatal intestinal pathology

Interleukin-23 (IL-23) responsive group 3 innate lymphoid cells (ILC3s) have been implicated in immune homeostasis and pathogenesis in the adult, but little is known about their roles in the newborn. Here we show that IL-23 promotes conversion of embryonic intestinal Lin(−)IL-23R(+)Thy1(+) cells int...

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Detalhes bibliográficos
Publicado no:Mucosal Immunol
Main Authors: Chen, Lili, He, Zhengxiang, Slinger, Erik, Bongers, Gerold, Lapenda, Taciana L.S., Pacer, Michelle E., Jiao, Jingjing, Beltrao, Monique F., Soto, Alan J., Harpaz, Noam, Gordon, Ronald E., Ochando, Jordi C., Oukka, Mohamed, Iuga, Alina Cornelia, Chensue, Stephen W., Blander, Julie Magarian, Furtado, Glaucia C., Lira, Sergio A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326561/
https://ncbi.nlm.nih.gov/pubmed/25160819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2014.77
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