A Role for the Epidermal Growth Factor Receptor Signaling in Development of Intestinal Serrated Polyps in Mice and Humans

BACKGROUND & AIMS: Epithelial cancers can be initiated by activating mutations in components of the mitogen-activated protein kinase (MAPK) signaling pathway such as BRAF, KRAS, or epidermal growth factor receptor (EGFR). Human intestinal serrated polyps are a heterogeneous group of benign lesio...

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Main Authors: Bongers, Gerold, Muniz, Luciana R., Pacer, Michelle E., Iuga, Alina C., Thirunarayanan, Nanthakumar, Slinger, Erik, Smit, Martine J., Reddy, E. Premkumar, Mayer, Lloyd, Furtado, Glaucia C., Harpaz, Noam, Lira, Sergio A.
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431560/
https://ncbi.nlm.nih.gov/pubmed/22643351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2012.05.034
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