The Effects of Screw Configuration and Polymeric Carriers on Hot-Melt Extruded Taste-Masked Formulations Incorporated into Orally Disintegrating Tablets

The primary aim of this research was to produce successfully taste masked formulations of Sildenafil Citrate (SC) using hot-melt extrusion (HME) technology. Multiple screw configurations and polymeric carriers were evaluated for their effects on taste masking efficiency, which was assessed by both E...

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Detalhes bibliográficos
Publicado no:J Pharm Sci
Main Authors: Morott, Joseph T., Pimparade, Manjeet, Park, Jun-Bom, Worley, Chelsea P., Majumdar, Soumyajit, Lian, Zhuoyang, Pinto, Elanor, Bi, Yunxia, Durig, Thomas, Repka, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326245/
https://ncbi.nlm.nih.gov/pubmed/25410968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.24262
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