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Pharmacokinetic model of unfractionated heparin during and after cardiopulmonary bypass in cardiac surgery

BACKGROUND: Unfractionated heparin (UFH) is widely used as a reversible anti-coagulant in cardiopulmonary bypass (CPB). However, the pharmacokinetic characteristics of UFH in CPB surgeries remain unknown because of the lack of means to directly determine plasma UFH concentrations. The aim of this st...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Jia, Zaishen, Tian, Ganzhong, Ren, Yupeng, Sun, Zhiquan, Lu, Wei, Hou, Xiaotong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326208/
https://ncbi.nlm.nih.gov/pubmed/25638272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0404-5
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