Pharmacokinetic Model for Cefuroxime Dosing during Cardiac Surgery under Cardiopulmonary Bypass

Cefuroxime (CXM) is an antibiotic recommended for surgical site infection prevention in cardiac surgery. However, the dosing regimens commonly used do not sustain therapeutic concentrations throughout surgery. The aim of this study was to conduct a population analysis of CXM pharmacokinetics (PK), a...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Lanoiselée, J., Zufferey, P. J., Hodin, S., Tamisier, N., Gergelé, L., Palao, J. C., Campisi, S., Molliex, S., Morel, J., Delavenne, X., Ollier, E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674023/
https://ncbi.nlm.nih.gov/pubmed/33020154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01687-20
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