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Pharmacokinetics of Epsilon-Aminocaproic Acid in Neonates: Undergoing Cardiac surgery with Cardiopulmonary Bypass

BACKGROUND: Antifibrinolytic medications such as epsilon-aminocaproic acid (EACA) are used in pediatric heart surgery to decrease surgical bleeding and transfusion. Dosing schemes for neonates are often based on adult regimens, or are simply empiric, in part due to the lack of neonatal pharmacokinet...

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Detalhes bibliográficos
Publicado no:Anesthesiology
Main Authors: Eaton, Michael P., Alfieris, George M, Sweeney, Dawn M, Angona, Ronald E, Cholette, Jill M, Venuto, Charles, Anderson, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882606/
https://ncbi.nlm.nih.gov/pubmed/25723765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000000616
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