Molecular Diagnosis of Fluoroquinolone Resistance in Mycobacterium tuberculosis

As a consequence of the use of fluoroquinolones (FQ), resistance to FQ has emerged, leading to cases of nearly untreatable and extensively drug-resistant tuberculosis. Mutations in DNA gyrase represent the main mechanism of FQ resistance. A full understanding of the pattern of mutations found in FQ-...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Bernard, Christine, Veziris, Nicolas, Brossier, Florence, Sougakoff, Wladimir, Jarlier, Vincent, Robert, Jérôme, Aubry, Alexandra
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
Matèries:
Mechanisms of Resistance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325825/
https://ncbi.nlm.nih.gov/pubmed/25534742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04058-14
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