Molecular Investigation of Resistance to Second-Line Injectable Drugs in Multidrug-Resistant Clinical Isolates of Mycobacterium tuberculosis in France

The second-line injectable drugs (SLID, i.e., amikacin, kanamycin, capreomycin) are key drugs for the treatment of multidrug-resistant tuberculosis. Mutations in rrs region 1400, tlyA, and eis promoter are associated with resistance to SLID, to capreomycin, and to kanamycin, respectively. In this st...

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Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Brossier, Florence, Pham, Anne, Bernard, Christine, Aubry, Alexandra, Jarlier, Vincent, Veziris, Nicolas, Sougakoff, Wladimir
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2017
Onderwerpen:
Mechanisms of Resistance
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278698/
https://ncbi.nlm.nih.gov/pubmed/27895017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01299-16
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