RNase L Targets Distinct Sites in Influenza A Virus RNAs

Influenza A virus (IAV) infections are influenced by type 1 interferon-mediated antiviral defenses and by viral countermeasures to these defenses. When IAV NS1 protein is disabled, RNase L restricts virus replication; however, the RNAs targeted for cleavage by RNase L under these conditions have not...

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Bibliographic Details
Published in:J Virol
Main Authors: Cooper, Daphne A., Banerjee, Shuvojit, Chakrabarti, Arindam, García-Sastre, Adolfo, Hesselberth, Jay R., Silverman, Robert H., Barton, David J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325751/
https://ncbi.nlm.nih.gov/pubmed/25540362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02953-14
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