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CREB and the CRTC co-activators: sensors for hormonal and metabolic signals

The cyclic AMP-responsive element-binding protein (CREB) is phosphorylated in response to a wide variety of signals, yet target gene transcription is only increased in a subset of cases. Recent studies indicate that CREB functions in concert with a family of latent cytoplasmic co-activators called c...

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Detalhes bibliográficos
Publicado no:Nat Rev Mol Cell Biol
Main Authors: Altarejos, Judith Y., Montminy, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324555/
https://ncbi.nlm.nih.gov/pubmed/21346730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3072
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