Heparan Sulfate Expression in the Neural Crest is Essential for Mouse Cardiogenesis

Impaired heparan sulfate (HS) synthesis in vertebrate development causes complex malformations due to the functional disruption of multiple HS-binding growth factors and morphogens. Here, we report developmental heart defects in mice bearing a targeted disruption of the HS-generating enzyme GlcNAc N...

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Publicado en:Matrix Biol
Main Authors: Pan, Yi, Carbe, Christian, Pickhinke, Ute, Kupich, Sabine, Ohlig, Stefanie, Frye, Maike, Seelige, Ruth, Pallerla, Srinivas R., Moon, Anne M., Lawrence, Roger, Esko, Jeffrey D., Zhang, Xin, Grobe, Kay
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324438/
https://ncbi.nlm.nih.gov/pubmed/24200809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2013.10.013
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