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Altered Heparan Sulfate Structure in Mice with Deleted NDST3 Gene Function

We report the generation and analysis of mutant mice bearing a targeted disruption of the heparan sulfate (HS)-modifying enzyme GlcNAc N-deacetylase/N-sulfotransferase 3 (NDST3). NDST3(-/-) mice develop normally, are fertile, and show only subtle hematological and behavioral abnormalities in agreeme...

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Detalhes bibliográficos
Main Authors: Pallerla, Srinivas R., Lawrence, Roger, Lewejohann, Lars, Pan, Yi, Fischer, Tobias, Schlomann, Uwe, Zhang, Xin, Esko, Jeffrey D., Grobe, Kay
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423263/
https://ncbi.nlm.nih.gov/pubmed/18385133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709774200
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