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Altered Heparan Sulfate Structure in Mice with Deleted NDST3 Gene Function
We report the generation and analysis of mutant mice bearing a targeted disruption of the heparan sulfate (HS)-modifying enzyme GlcNAc N-deacetylase/N-sulfotransferase 3 (NDST3). NDST3(-/-) mice develop normally, are fertile, and show only subtle hematological and behavioral abnormalities in agreeme...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2423263/ https://ncbi.nlm.nih.gov/pubmed/18385133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709774200 |
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