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Heparan Sulfate Regulates VEGF(165)- and VEGF(121)-mediated Vascular Hyperpermeability

VEGF was first described as vascular permeability factor, a potent inducer of vascular leakage. Genetic evidence indicates that VEGF-stimulated endothelial proliferation in vitro and angiogenesis in vivo depend on heparan sulfate, but a requirement for heparan sulfate in vascular hyperpermeability h...

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Autors principals: Xu, Ding, Fuster, Mark M., Lawrence, Roger, Esko, Jeffrey D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013032/
https://ncbi.nlm.nih.gov/pubmed/20974861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.177006
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