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N-Sulfation of Heparan Sulfate Regulates Early Branching Events in the Developing Mammary Gland
Branching morphogenesis, a fundamental process in the development of epithelial organs (e.g. breast, kidney, lung, salivary gland, prostate, pancreas), is in part dependent on sulfation of heparan sulfate proteoglycans. Proper sulfation is mediated by biosynthetic enzymes, including exostosin-2 (Ext...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3516752/ https://ncbi.nlm.nih.gov/pubmed/23060443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.423327 |
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