N-Sulfation of Heparan Sulfate Regulates Early Branching Events in the Developing Mammary Gland

Branching morphogenesis, a fundamental process in the development of epithelial organs (e.g. breast, kidney, lung, salivary gland, prostate, pancreas), is in part dependent on sulfation of heparan sulfate proteoglycans. Proper sulfation is mediated by biosynthetic enzymes, including exostosin-2 (Ext...

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Detaylı Bibliyografya
Asıl Yazarlar: Bush, Kevin T., Crawford, Brett E., Garner, Omai B., Nigam, Kabir B., Esko, Jeffrey D., Nigam, Sanjay K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2012
Konular:
Glycobiology and Extracellular Matrices
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3516752/
https://ncbi.nlm.nih.gov/pubmed/23060443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.423327
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