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Cerebral hypoplasia and craniofacial defects in mice lacking heparan sulfate Ndst1 gene function
Mutant mice bearing a targeted disruption of the heparan sulfate (HS) modifying enzyme GlcNAc N-deacetylase/N-sulfotransferase 1 (Ndst1) exhibit severe developmental defects of the forebrain and forebrain-derived structures, including cerebral hypoplasia, lack of olfactory bulbs, eye defects and axo...
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| Udgivet i: | Development |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7851831/ https://ncbi.nlm.nih.gov/pubmed/16020517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.01935 |
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