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An Emerging Role of Sonic Hedgehog Shedding as a Modulator of Heparan Sulfate Interactions

Major developmental morphogens of the Hedgehog (Hh) family act at short range and long range to direct cell fate decisions in vertebrate and invertebrate tissues. To this end, Hhs are released from local sources and act at a distance on target cells that express the Hh receptor Patched. However, mor...

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Detalhes bibliográficos
Main Authors: Ohlig, Stefanie, Pickhinke, Ute, Sirko, Svetlana, Bandari, Shyam, Hoffmann, Daniel, Dreier, Rita, Farshi, Pershang, Götz, Magdalena, Grobe, Kay
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527956/
https://ncbi.nlm.nih.gov/pubmed/23118222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.356667
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