An Emerging Role of Sonic Hedgehog Shedding as a Modulator of Heparan Sulfate Interactions

Major developmental morphogens of the Hedgehog (Hh) family act at short range and long range to direct cell fate decisions in vertebrate and invertebrate tissues. To this end, Hhs are released from local sources and act at a distance on target cells that express the Hh receptor Patched. However, mor...

Full description

Saved in:
Bibliographic Details
Main Authors: Ohlig, Stefanie, Pickhinke, Ute, Sirko, Svetlana, Bandari, Shyam, Hoffmann, Daniel, Dreier, Rita, Farshi, Pershang, Götz, Magdalena, Grobe, Kay
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3527956/
https://ncbi.nlm.nih.gov/pubmed/23118222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.356667
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items