Systematic Optimization of Long Gradient Chromatography Mass Spectrometry for Deep Analysis of Brain Proteome

[Image: see text] The development of high-resolution liquid chromatography (LC) is essential for improving the sensitivity and throughput of mass spectrometry (MS)-based proteomics. Here we present systematic optimization of a long gradient LC–MS/MS platform to enhance protein identification from a...

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Bibliografske podrobnosti
izdano v:J Proteome Res
Main Authors: Wang, Hong, Yang, Yanling, Li, Yuxin, Bai, Bing, Wang, Xusheng, Tan, Haiyan, Liu, Tao, Beach, Thomas G., Peng, Junmin, Wu, Zhiping
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2014
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324436/
https://ncbi.nlm.nih.gov/pubmed/25455107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr500882h
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