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Liquid chromatography-tandem mass spectrometry assay for the simultaneous quantification of simvastatin, lovastatin, atorvastatin, and their major metabolites in human plasma
Millions of individuals are treated with a variety of statins that are metabolized to a variety of active metabolites. A single assay capable of simultaneously quantifying commonly used statins and their major metabolites has not been previously reported. Herein we describe the development and valid...
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| 出版年: | J Chromatogr B Analyt Technol Biomed Life Sci |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4324004/ https://ncbi.nlm.nih.gov/pubmed/25612772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2014.12.029 |
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