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Rapid and Simultaneous Quantification of Levetiracetam and Its Carboxylic Metabolite in Human Plasma by Liquid Chromatography Tandem Mass Spectrometry

A simple liquid chromatography tandem mass spectrometry method was developed and validated according to the guidelines of the US Food and Drug Administration and the European Medicines Agency for a simultaneous quantification of levetiracetam (LEV) and its metabolite, UCB L057 in the plasma of patie...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yeap, Li-Ling, Lo, Yoke-Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223074/
https://ncbi.nlm.nih.gov/pubmed/25375249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111544
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