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Liquid chromatography-tandem mass spectrometry assay for the simultaneous quantification of simvastatin, lovastatin, atorvastatin, and their major metabolites in human plasma
Millions of individuals are treated with a variety of statins that are metabolized to a variety of active metabolites. A single assay capable of simultaneously quantifying commonly used statins and their major metabolites has not been previously reported. Herein we describe the development and valid...
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| Publicado no: | J Chromatogr B Analyt Technol Biomed Life Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4324004/ https://ncbi.nlm.nih.gov/pubmed/25612772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2014.12.029 |
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