Simultaneous quantitation of atorvastatin and its two active metabolites in human plasma by liquid chromatography/(–) electrospray tandem mass spectrometry

A sensitive, accurate and selective liquid chromatography–tandem mass spectrometry method (LC–MS/MS) was developed and validated for the simultaneous quantitation of atorvastatin (AT) and its equipotent hydroxyl metabolites, 2-hydroxy atorvastatin (2-AT) and 4-hydroxy atorvastatin (4-AT), in human p...

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Détails bibliographiques
Publié dans:J Pharm Anal
Auteurs principaux: Partani, Pankaj, Verma, S. Manaswita, Gurule, Sanjay, Khuroo, Arshad, Monif, Tausif
Format: Artigo
Langue:Inglês
Publié: Xi'an Jiaotong University 2014
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5761050/
https://ncbi.nlm.nih.gov/pubmed/29403866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2013.09.007
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