Virological and Preclinical Characterization of a Dendritic Cell Targeting, Integration-deficient Lentiviral Vector for Cancer Immunotherapy

Dendritic cells (DCs) are essential antigen-presenting cells for the initiation of cytotoxic T-cell responses and therefore attractive targets for cancer immunotherapy. We have developed an integration-deficient lentiviral vector termed ID-VP02 that is designed to deliver antigen-encoding nucleic ac...

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Detalhes bibliográficos
Publicado no:J Immunother
Main Authors: Odegard, Jared M., Kelley-Clarke, Brenna, Tareen, Semih U., Campbell, David J., Flynn, Patrick A., Nicolai, Christopher J., Slough, Megan M., Vin, Chintan D., McGowan, Patrick J., Nelson, Lisa T., ter Meulen, Jan, Dubensky, Thomas W., Robbins, Scott H.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2015
Assuntos:
Basic Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323576/
https://ncbi.nlm.nih.gov/pubmed/25658613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0000000000000067
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