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A Rev-Independent gag/pol Eliminates Detectable psi-gag Recombination in Lentiviral Vectors
Lentiviral vectors (LVs) are being developed for clinical use in humans for applications including gene therapy and immunotherapy. A safety concern for use of LVs in humans is the generation of replication-competent lentivirus (RCL), which may arise due to recombination between the split genomes of...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3869434/ https://ncbi.nlm.nih.gov/pubmed/24380052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/biores.2013.0037 |
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