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RNA-primed DNA synthesis: specific catalysis by HeLa cell DNA polymerase alpha.

We have analyzed and compared the responses of the three major HeLa cell DNA polymerases (alpha, beta, and gamma) to a HeLa DNA template with short RNA or DNA primers hybridized to it. Only DNA polymerase alpha is able to synthesize DNA covalently bonded to the RNA primer via a 3' yields 5' phosphod...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Spadari, S, Weissbach, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1975
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC432340/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1054833/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.72.2.503
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