Synchronization of HeLa cell cultures by inhibition of DNA polymerase alpha with aphidicolin.

Both the inhibitory effect of aphidicolin on the replicative alpha-polymerase and the reversibility of its action in vivo (Pedrali-Noy & Spadari, 1979, Biochem. Biophys. Res. Commun. 88, 1194-2002) allow the synchronization of cells in culture. Aphidicolin prevents G1 cells from entering the DNA...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Pedrali-Noy, G, Spadari, S, Miller-Faurès, A, Miller, A O, Kruppa, J, Koch, G
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1980
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC327273/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6775308/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/8.2.377
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