RNA-primed DNA synthesis: specific catalysis by HeLa cell DNA polymerase alpha.
We have analyzed and compared the responses of the three major HeLa cell DNA polymerases (alpha, beta, and gamma) to a HeLa DNA template with short RNA or DNA primers hybridized to it. Only DNA polymerase alpha is able to synthesize DNA covalently bonded to the RNA primer via a 3' yields 5' phosphod...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1975
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC432340/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1054833/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.72.2.503 |
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